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Created: 05 July 2022

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• VOL 2, No. 2 (2022)

Testicular neoplasms cause diagnostic difficulties for clinical and laboratory diagnostics in young and middle-aged men.
Seminoma refers to germ-cell tumors (GCTs) and is the most common cancer of this localization. But the timely and correct diagnostics by non-invasive technologies is still difficult. The clinical case clarifies the innovative techniques by Sperm
Sediment Cytology (SSC) as the non-invasive diagnostic approach resulting in excellent tumor cells detection. While a non-invasive conventional diagnostics and laboratory examination are of low diagnostic value this method can help oncologists and urologists for a confident judgment about the nature of the process and the timely choice of further treatment tactics.

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Created: 31 March 2022

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• VOL 2, No. 1 (2022)

GISTs are the most common mesenchymal tumors of the stomach, however, they are rare among all tumors of the gastrointestinal tract. In this clinical case, the use of an integrated approach in the morphological diagnosis of gastric GIST based on fine needle biopsy material was demonstrated.

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Created: 31 March 2022

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• VOL 2, No. 1 (2022)

A case of severe anemia of mixed genesis is presented. The clinical picture of the disease is described, the data of laboratory investigations are given. The interest of this case for attending physicians and employees of clinical diagnostic laboratories (CDL) is due to significant discrepancies between the results of blood analysis according to automatic analysis performed using a hematology analyzer and the data of light microscopy of a stained blood smear. Various morphological changes were found in the stained blood smear, which contradicted relatively normal erythrocyte parameters (MСV, MСН, RDW) and the absence of any flags according to the hematological analyzer.
The problems of using hematological analyzer data as a basis for differential diagnosis of anemia with various disorders of erythrocyte and leukocyte morphology, especially when using artificial intelligence for decision-making, are discussed.