Laboratory and Clinical Medicine. Pharmacy

Scientific and practical quarterly peer-reviewed journal

ISSN 2712-9330 (Online)

  • Continuous numbering: 18
  • Pages: 33-39
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Heading: Original Articles

Complex processing of raw materials is a rational way to use the resources of medicinal plants. It was of interest to evaluate the expediency of using meal obtained after juice extraction from the grass of the common cuff, freshly harvested as a plant substance with the potential of a prebiotic. The purpose of this study was to study and evaluate the potential of bacteriotropic activity of common grass cuff meal. The chemical composition of meal samples contains flavonoids, tannins, polysaccharides, free amino acids and minerals capable of stimulating the growth and development of microorganisms. The stimulating effect of meal on the culture of lactobacilli is shown by a significant decrease in glucose levels in all samples compared with the control. The culture of lactobacilli reacted to the introduction of an infusion of grass meal into the nutrient medium by increasing the accumulation of biomass. It was found that all samples of the meal infusion have the property of inhibition with a pronounced dose-dependent effect on changing the luminescence level of the E.coli lum+ strain in the bioluminescence inhibition test when exposed for 4 hours. In the course of the research, the bacteriotropic properties of meal from grass cuffs have been identified, which determine its prospects for the correction and prevention of dysbiotic conditions by improving the functional potential of the human microbiota or farm animals and poultry. Within the framework of rational use of resources, it seems advisable to use meal as a plant substance with the potential of a prebiotic.
Elena V. Zorina – Candidate of Pharmaceutical Sciences, Associate Professor of the Botany and Pharmaceutical Biology Department, Perm State Pharmaceutical Academy, Perm, Russia.
Valery A. Neschislyaev – Doctor of Medical Sciences, Associate Professor, Professor of the Industrial Technology of Medicines with a Course in Biotechnology Department, Perm State Pharmaceutical Academy, Perm, Russia.
Anastasia A. Suvorova – the graduate of the Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation, Perm, Russia.
Yuri N. Maslov – Doctor of Medical Sciences, Professor, Professor of the Microbiology and Virology Department, Perm State Medical University named after academician E.A. Vagner, Perm, Russia.
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DOI: 10.14489/lcmp.2025.04.pp.033-039
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Zorina EV, Neschislyaev VA, Suvorova AA, Maslov YuN. Bacteriotropic activity of meal of alchemilla vulgaris herb. Laboratory and Clinical Medicine. Pharmacy. 2025;5(4):33-39. (In Russ). DOI: 10.14489/lcmp. 2025.04.pp.033-039