The paper refers the outcomes of international research in post-acute sequelae of COVID-19 (PASC). It is necessary to emphasize the pathophysiological mechanisms of PASC in PCR-negative patients recovered from COVID-19: long-persistent hyperactivated congenital immunity, hyper-inflammation, hyper-coagulation, hypo-fibrinolysis, micro-thrombosis, antibodies formation, and multiplе human organ dysfunction. The challenges as well as possibilities in laboratory diagnostics of PASC complication have been noted.
Larisa V. Mukhomorova – senior medical advisor, DIAKON JSC, Pushchino, Moscow Region, Russia E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Vasily V. Velkov – PhD, chief scientific officer, DIAKON JSC, Pushchino, Moscow Region, Russia E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
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