Laboratory and Clinical Medicine. Pharmacy

Scientific and practical quarterly peer-reviewed journal

 

ISSN 2712-9330 (Online)

  • Continuous numbering: 4
  • Pages: 67-76
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Heading: Clinical Case

Meningoangiomatosis is a rare benign lesion characterized by proliferation of blood vessels and meningothelial cells, often fusiform, which is sometimes accompanied by cortical dysplasia. Proliferation of vascular cells, pronounced cellularity and reactive gliosis may be misdiagnosed by a pathologist as invasive angiomatous meninigioma, which may lead to the postoperative radiation therapy. Immunohistochemical examination can help in the differentiation and exclusion of other diseases, such as meningioma and schwannoma. There are certain histopathological and clinical features of angiomatous meningioma, i.e. meningiomas whose vascular component exceeds 50 % of the total tumor area. Accurate differential diagnosis of meningoangiomatosis and angiomatous meningioma is important, since the correct recognition of pathology will not lead to overly aggressive postoperative treatment, as radiation therapy or chemotherapeutic treatment as in the case of meningioma.

Alexandra V. Nikanorova – resident pathologist, Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Olga I. Patsap – MD, PhD, Head of Pathology Department, Federal Center of Brain Research and Neurotechnologies FMBA, Researcher at the Scientific and Educational Resource Center for Innovative Technologies of Immunophenotyping, Digital Spatial Profiling and Ultrastructural Analysis (Molecular Morphology), Peoples' Friendship University of Russia, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Ilya V. Grigoriev – MD, PhD, neurosurgeon, Neurosurgical Department, Federal Center of Brain Research and Neurotechnologies FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Semyon A. Melchenko – neurosurgeon, Neurosurgical Department, Federal Center of Brain Research and Neurotechnologies FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Ilya V. Senko – MD, PhD, neurosurgeon, chief of department, Neurosurgical Department, Federal Center of Brain Research and Neurotechnologies FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Renata A. Balgishieva – neurologist, JSC “MEDSI Group of Companies”, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..
Maria A. Smirnova – specialist of the Department of accounting and organization of medical services of the Federal State Budgetary Institution FTSN FMBA of Russia, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it..

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DOI: 10.14489/lcmp.2022.02.pp.067-076
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Nikanorova AV, Patsap OI, Grigoriev IV, Melchenko SA, Senko IV, Balgishieva RA, Smirnova MA, Meningoangiomatosis and angiomatous meningioma: quiz in differential diagnosis. A series of cases. Laboratory and Clinical Medicine. Pharmacy. 2022;2(2):67-76. (In Russ). DOI: 10.14489/lcmp.2022.02.pp.067-076