Laboratory and Clinical Medicine. Pharmacy

Scientific and practical quarterly peer-reviewed journal

 

ISSN 2712-9330 (Online)

VOL 1, No. 2 (2021)

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    Critical Review

  • DOCTOR’S SELF-PRESENTATION IN ONLINE COMMUNICATION

    • Pages: 4-22
    • Views: 835
    The doctor is a way of life, which includes monitoring and correction of them-self presentation continuously. The physician is one of the socially significant and language-active professions. The language activity of doctors in the Internet
    is determined by their consciousness and communicative behavior in various genres of social media – a blog, a forum,
    a social network, a personal website, etc. Evidence indicates that electronic communication can improve health outcomes, for example by promoting professional development, emphasizing self-presentation, and also highlighting linguistic
    personality of physicians, which is based on verbal-non-verbal behavior. However, discussion of the dangers of these technologies in medicine has overshadowed the consideration of positive applications. Online communication has introduced profound questions about confidentiality, professionalism, and other issues of ethical and legal regulation for healthcare professionals. Understanding that will help to avoid mistakes, thereby maintaining a high level of the doctor's professional image.
  • Clinical Lectures

  • CLINICAL AND LABORATORY EXAMINATION OF SYNOVIAL FLUID IN THE JOINT DISEASES DIAGNOSTICS. PART 1

    • Pages: 23-33
    • Views: 329
    Synovial fluid examination plays the important role in diagnosis and treatment of joint diseases. Nowadays it presents a substantial challenge in clinical and lab settings because of lack of manuals for the examination and processing
    of synovial fluid. It needed cross-disciplinary approach between orthopedic and trauma surgeons, rheumatologists, general practitioners, and clinical lab specialists to achieve the diagnostic and treatment spot-on goals in time. It is become incredibly important to develop the standard procedures for assessment of synovial fluid and its implementation into the practice for clinical diagnostic laboratories.
  • Original Articles

  • PROBLEMATIC FEATURES OF THE REHABILITATION PROCESS AT ITS MEDICAL STAGE

    • Pages: 34-46
    • Views: 362
    Rehabilitation, as a system of medical, psychological, socio-economic measures aimed at eliminating or possibly fully compensating for disabilities, is of great importance in the social protection of disabled people and the prevention of disability. In the article, based on the analysis of the cur-rent legislative and regulatory acts, scientific articles on the topic
    of rehabilitation and our own research, it is shown that there is no proper correspondence between the theory of rehabilitation, regulations and the organization of the rehabilitation process in medical institutions. The authors have proposed
    a number of ideas and activities that, in their opinion, should help in resolving existing inconsistencies and contradictions.
  • THE INFLUENCE OF TRAINING SESSIONS OF NORTHERN (SCANDINAVIAN) WALKING ON THE PARAMETERS OF THE FUNCTIONAL STATE OF MEDICAL UNIVERSITY STUDENTS

    • Pages: 47-53
    • Views: 663
    In this article, the purpose of the study was a comparative analysis of the parameters of the functional state of the body
    of students under the systematic influence of moderate physical exertion of northern (Scandinavian) walking. The study included 85 second-year students of the Volga Research Medical University. To visualize the indicators of the state
    of the body, the system of sports testing “MedicalSoft” was used. The functional status of the students' organism was studied before the start of Nordic (Scandinavian) walking classes, and after the completion of a two-month course of exposure to metered physical exertion. The analysis of the data obtained was carried out in accordance with the age standards that were formed by the developers of the equipment. It is established that systematic health-improving and training loads
    favorably affect the state of the body of the subjects, increasing its adaptive capabilities, which is confirmed by dynamic changes in the values of integral indicators.
  • Clinical Case

  • CYTOLOGICAL DIAGNOSTICS OF MERKEL CELL CARCINOMA (PRIMARY NEURO-ENDOCRINE SKIN CANCER) IN THE MATERIAL OF A SUPERFICIAL SHAVE BIOPSY

    • Pages: 54-58
    • Views: 360
    Merkel cell carcinoma is a rare malignant primary skin tumor with epithelial and neuroendocrine differentiation.
    In the presented diagnostic case, the possibility of a cytological method in this material is a scarification biopsy.
  • DIAGNOSTIC CAPABILITIES OF FINE NEEDLE ASPIRATION OF LYMPH NODES METASTASES OF PRIMARY PULMONARY LYMPHOEPITHELIAL CARCINOMAS

    Autors: V. G. Kravtsov
    • Pages: 59-64
    • Views: 375
    Introduction. Primary pulmonary lymphoepithelial carcinoma is a poorly differentiated squamous cell carcinoma admixed with variable amounts of lymphoplasmacytic infiltrate, frequently associated with EBV. It is a rare cancer and have a better prognosis than other non-small cell lung cancer. The tumor can mimic metastatic non-keratinizing SCC of the naso-pharynx, poorly differentiated non-small cell carcinoma and NUT carcinoma arising in the lung, and non-Hodgkin
    lymphomas.
    Materials and methods. A 75-year-old man presented with peripheral mass of left lower lobe, maximal diameter was 5.1 cm, involving lingula and medial pleura, with mediastinal, and retroperitoneal lymphadenopathy revealed by computer tomography. Fine needle aspiration-EBUS was performed from hilar and interlobar lymph nodes. Papanicolaou smears
    and cell blocks were prepared. Additional CT-guided cor-needle biopsy and FNA were performed from lung lesion later.
    Results. A few large malignant epithelial cells, consistent with non-small lung cancer, were found on a background
    of lymphocytes in fine-needle aspiration from lymph nodes. Immunostain results: Pan-CK (AE1/AE3), p63 and Ki67
    were positive in malignant cells, leukocyte common antigen (CD45) was positive in lymphocytes (negative in tumor cells), and negative markers were TTF1, chromogranin and synaptophysin. Cytological diagnosis was metastatic non-small lung cancer, favor squamous cell carcinoma. Biopsy and aspiration from left lung showed syncytial groups of large malignant epithelial cells with scant cytoplasm and prominent nucleoli on a background of prominent inflammatory infiltrate,
    consistent with lymphoepithelial carcinoma.
    Conclusion. It is impossible to correctly diagnose metastasis of lymphoepithelial carcinoma in lymph node by FNA only without FNA or biopsy of primary lesion, because cytological features and immunostains are identical to non-keratinizing squamous cell carcinoma.
  • Review Articles

  • LABORATORY DIAGNOSTICS OF MALE INFERTILITY. BIOMARKERS AND METHODS. Part II

    • Pages: 65-79
    • Views: 631
    The new paradigm have been arise concerning to samples, markers and methods for assessment of male infertility. Nowadays, a sample “semen” and “sperm sediment” take a key role in examination and management of the subfertile couple. The advantages of sample “semen” such as non-invasive painless procedure as well as the wider range of diagnostic
    findings by number of methods (cytology, molecular and cultural) highlight the increasly importance of this diagnostic approach in comparison with conventional ones – prostate secretion and urethral scraping which obtained by invasive
    procedures – by massage and damaging a mucus membrane, respectively.
    According to the Russian register this review also presents the current situation with the work list of kits and devices for assessment of male infertility and inflammatory of male accessory glands.