Laboratory and Clinical Medicine. Pharmacy

Scientific and practical quarterly peer-reviewed journal

 

ISSN 2712-9330 (Online)

  • Continuous numbering: 14
  • Pages: 47-54
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Heading: Clinical Case

Melanoma is one of the most difficult skin tumours to diagnose cytologically and histologically. The accuracy of the examination results in the diagnostic process with cutaneous melanoma depends on strict compliance with the technological procedures of the pre-analytical extra-laboratory stage – adequacy of the obtained material; pre-analytical laboratory stage – correct sample preparation and quality staining of biopsy and surgical material; analytical laboratory stage – expertise of the pathologist in dermatopathology; post-analytical stage – selection of the necessary further diagnostic tactics, namely, the implementation of ancillary procedures; and the use of auxiliary procedures. The key role is given to interdisciplinary interaction between cytologists and pathologists in verification of melanoma diagnosis.
Valeria N. Vysotskaya – faculty, International Cytology School&Innovatory Medical School, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Igar I. Haiduk – pathologist, LLC ‘UNIM’, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Zhanna Yu. Sapozhkova – MD, PhD, International Cytology School&Innovatory Medical School, Head, Senior Lecturer, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Karine T. Kasoyan – MD, PhD, Assistant Professor, Department of Clinical Laboratory Diagnostics, Russian Medical Academy of Continuous Professional Education, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
1. AD Kaprin, i dr., red. Zlokachestvennye novoobrazovaniya v Rossii v 2022 godu (zabolevaemost i smertnost) M.: MNIOI im. PA Gercena ? filial FGBU “NMIC radiologii” Minzdrava Rossii; 2023. Available at: https://oms66.ru/upload/iblock/52d/6u9uo6ajmjooxfl8m738lck2qzog7lza/zno_2022.pdf. Accessed: 19 Okt 2024.
2. Whiteman DC, Green AC, Olsen CM. The growing burden of invasive melanoma: projections of incidence rates and numbers of new cases in six susceptible populations to 2031. Journal of Investigative Dermatology. 2016; 136:1161-71. DOI: 10.1016/j.jid.2016.01.035
3. Davis LE; Shalin SC; Tackett AJ. Current state of melanoma diagnosis and treatment. Cancer Biology & Therapy. 2019;20:1366-79. DOI: 10.1080/15384047.2019.1640032
4. Garanina OE, Samoylenko IV, Shlivko IL, et al. Non-invasive diagnostic techniques for skin tumors and their potential for use in skin melanoma screening: a systematic literature review. Meditsinskiy sovet = Medical Council. 2020;(9):102-20. (In Russ). DOI: 10.21518/2079-701X-2020-9-102-120
5. Abramov ME, Aliev MD, Banov SM, i dr. Melanoma kozhi i slizistyh obolochek. Klinicheskie rekomendacii. 2023 g. Available at: https://cr.minzdrav.gov.ru/recomend/546_3 Accessed: 19 Okt 2024. (In Russ).
6. Order of the Ministry of Health of the Russian Federation dated March 11, 2021 N 194n “Ob utverzhdenii standartov medicinskoj pomoshi vzroslym pri melanome kozhi i slizistyh obolochek”. Available at: http://publication.pravo.gov.ru/document/0001202104130042. Accessed: 19 Okt 2024. (In Russ).
7. Novik VI, Dreval DA. Cytological diagnosis as a method of screening of premalignant melanocytic tumors and early forms of skin melanoma. Voprosy onkologii. 2018;64(3):384-7. (In Russ.) DOI: 10.37469/0507-3758-2018-64-3-384-387
8. Sokolova VK. Citologicheskaya diagnostika opuholevyh i neopuholevyh porazhenij kozhi. Laboratoriya klinicheskoj citologii FGBU Rossijskij onkologicheskij nauchnyj centr im. NN Blohina. M.; 2015. (In Russ).
9. Michael T Sheaff, Naveena Singh. Cytopathology. Springer-Verlag London; 2013. DOI 10.1007/978-1-4471-2419-1
10. Aliev MD, Alieva SB, Alymov YuV, i dr. Bazalnokletochnyj rak kozhi. Klinicheskie rekomendacii. 2024 g. Available at: https://cr.minzdrav.gov.ru/recomend/467_3. Accessed: 19 Okt 2024. (In Russ).
11. Dolgov VV, Menshikov VV, red. Klinicheskaya laboratornaya diagnostika. Nacionalnoe rukovodstvo. V 2 tomah. T. 1: GEOTAR-Media; 2013.(In Russ.).
12. Shapiro NA, Batoroev YuK, Dvornichenko VV. Cytological diagnosis of skin diseases. Color atlas. Moscow-Irkutsk: «Reprocenter M»; 2015. (In Russ.).

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DOI: 10.14489/lcmp.2024.04.pp.047-054
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Vysotskaya VN, Haiduk II, Sapozhkova ZhYu, Kasoyan KT. Multidisciplinary approach to morphological diagnosis of melanoma. Case report. Laboratory and Clinical Medicine. Pharmacy. 2024;4(4):47-54. (In Russ). DOI: 10.14489/lcmp.2024.04.pp.047-054